Scream is an American murder mystery and slasher franchise that includes six films, a television series, merchandise, and games. The first four films were directed by Wes Craven. The series was created by Kevin Williamson, who wrote the first two films and the fourth; Ehren Kruger wrote the third. The fifth and sixth installments were directed by Matt Bettinelli-Olpin and Tyler Gillett, with Guy Busick and James Vanderbilt serving as writers and Williamson returning as executive producer. Dimension Films produced the first four films. Spyglass Media Group took over the rights from the fifth film on with Paramount Pictures distributing. The film series has grossed over US$900 million at the global box office.

Neve Campbell, Courteney Cox, David Arquette, and Roger L. Jackson (who voices the various Ghostface killers) starred in the first five films. Cox and Jackson reprised their roles for the sixth and are the only cast members to feature in all films to date with Cox also being the only actress to appear in six consecutive films of a horror franchise.

Hayden Panettiere stars in the fourth and sixth films, while Melissa Barrera, Jenna Ortega, Mason Gooding, and Jasmin Savoy Brown star in the fifth and sixth. Jamie Kennedy and Liev Schreiber feature in the first three films, Skeet Ulrich stars in the first and cameos in the fifth and sixth installments, Marley Shelton appears in the fourth and fifth, and Jack Quaid stars in the fifth and cameos in the sixth. Additionally, Heather Matarazzo makes cameo appearances in the third and fifth films, as does Nancy O’Dell in the second, third and fourth. Having appeared in the iconic opening scene of the first film and on its poster, Drew Barrymore is strongly associated with the franchise. The series has also featured many notable actors making single-film appearances in supporting cast roles or as cameos.

Scream (1996), Scream 2 (1997), Scream (2022), and Scream VI (2023) received high praise from critic